Description

Montirelin is a synthetic thyrotropin-releasing hormone (TRH) analog with significant research and pharmaceutical applications. This compound is valued for its stability and potent biological activity, making it a critical intermediate and reference standard in neuroendocrine research. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions focused on central nervous system disorders and diagnostic applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced neuroactive peptides and potential therapeutic agents.
• Neuroendocrine Research: Used as a reference standard and tool compound to study the hypothalamic-pituitary-thyroid axis and TRH receptor interactions.
• Diagnostic Agent Development: Investigated for use in diagnostic tests to assess pituitary and thyroid gland function.
• Biochemical Research: Employed in studies of peptide stability, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Provides a high-purity benchmark for analytical method development and validation in quality control laboratories.

Basic Information

Item	Detail
Product Name	Montirelin
CAS No.	90243-66-6
Molecular Formula	C16H22N6O4
Molecular Weight	362.39 g/mol
Synonyms	L-Pyroglutamyl-L-histidyl-L-prolinamide; CG 3703; TRH-T; Thyrotropin-Releasing Hormone, 3-Methyl Analog; Montirelin Acetate; 3-Methyl-His-TRH; Lopremone; (S)-5-Oxo-1-((S)-1-((S)-2-amino-1-oxo-3-(pyrrolidin-1-yl)propyl)-1H-imidazol-4-yl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Montirelin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent controls for residual solvents and related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.