Description

Bis(Benzylpenicilloyl)-1,6-Diaminohexane is a specialized penicilloyl hapten derivative, a critical intermediate in immunological research and diagnostic development. Its primary value lies in its role as a precise chemical probe for studying penicillin allergy and developing sensitive immunoassays. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and clinical diagnostics sectors who require high-purity, well-characterized haptens for antibody production and assay standardization.

Application

• Penicillin Allergy Research: Serves as a key hapten for the synthesis of immunogens to raise specific antibodies against the benzylpenicilloyl epitope, the major antigenic determinant in penicillin hypersensitivity.
• Diagnostic Immunoassay Development: Used as a coating antigen or a conjugate in enzyme-linked immunosorbent assays (ELISA) and other immunoassays designed to detect penicillin-specific IgE and IgG antibodies in patient sera.
• Reference Standard: Acts as a certified reference material (CRM) for the qualification and validation of analytical methods used in immunology and allergy testing laboratories.
• Bioconjugation & Probe Synthesis: Utilized as a building block for creating advanced molecular probes and carrier protein conjugates for immunological studies and diagnostic kit components.
• Pharmaceutical Impurity Profiling: Employed in studies investigating the mechanism of drug hypersensitivity and the characterization of drug-protein adducts related to β-lactam antibiotics.

Basic Information

Product Name	Bis(Benzylpenicilloyl)-1,6-Diaminohexane
CAS No.	21291-04-3
Molecular Formula	C34H44N4O6S2
Molecular Weight	668.86 g/mol
Synonyms	1,6-Hexanediamine, N,N'-bis[(phenylacetyl)amino]penicilloyl]-; BPO-HMD; Benzylpenicilloyl Hexamethylenediamine; Penicilloyl Hapten; BPO-HA; N,N'-Bis(benzylpenicilloyl)-1,6-hexanediamine; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with hexane-1,6-diamine (2:1)
EINECS	Contact for details

Quality Control

Our Bis(Benzylpenicilloyl)-1,6-Diaminohexane is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR). A detailed Certificate of Analysis (COA) providing full specification data is supplied with every shipment, supporting compliance with GLP and research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.