Description

Tetragastrin CAS NO 1947-37-1 is a synthetic tetrapeptide fragment of the gastrin hormone, known for its potent stimulatory effect on gastric acid secretion. This compound is a critical research tool and pharmaceutical intermediate for studying gastrointestinal physiology and developing therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on endocrinology and digestive system drug development.

Application

• Pharmacological Research: Used as a standard agonist to study gastrin receptor (CCK2R) signaling pathways and gastric acid secretion mechanisms in vitro and in vivo.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of gastrointestinal-targeted drugs.
• Diagnostic Agent Research: Investigated for use in diagnostic tests to assess gastric secretory function and parietal cell activity.
• Biochemical Studies: Employed in biochemical assays to understand peptide hormone structure-activity relationships and receptor binding kinetics.
• Academic Research: A fundamental reagent in university and institutional labs for teaching and advanced research in endocrinology and peptide chemistry.

Basic Information

Product Name	Tetragastrin
CAS No.	1947-37-1
Molecular Formula	C26H37N7O7
Molecular Weight	559.62 g/mol
Synonyms	N-[(1,1-Dimethylethoxy)carbonyl]-β-alanyl-L-tryptophyl-L-methionyl-L-aspartic acid; Boc-β-Ala-Trp-Met-Asp-OH; Gastrin I (1-4); Gastrin Tetrapeptide; Trp-Met-Asp-Phe-NH2 (common sequence reference); H-βAla-Trp-Met-Asp-OH; NSC 113792; CCK-4 (Cholecystokinin Tetrapeptide) analog
EINECS	217-773-7

Quality Control

Our Tetragastrin is produced under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.