Description

Binodenoson is a selective adenosine A2A receptor agonist, a high-purity pharmaceutical intermediate and research chemical. Its primary value lies in its role as a potent coronary vasodilator, making it a critical compound for cardiac stress testing and cardiovascular research. This product is essential for pharmaceutical R&D teams, diagnostic manufacturers, and academic researchers focused on cardiology and receptor pharmacology. We supply Binodenoson CAS NO 144348-08-3 to the global market with a commitment to consistent quality and reliable supply chain integrity.

Application

• Pharmaceutical Active Ingredient (API): Key intermediate in the synthesis of cardiac diagnostic agents.
• Cardiac Stress Testing: Used as a pharmacological stress agent in myocardial perfusion imaging as an alternative to physical exercise.
• Cardiovascular Research: Vital tool for studying adenosine A2A receptor function, coronary blood flow, and vasodilation mechanisms.
• Diagnostic Kit Manufacturing: Component in kits for non-invasive assessment of coronary artery disease.
• Preclinical Studies: Employed in animal models to evaluate cardiac function and ischemic heart disease.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical production.

Basic Information

Product Name	Binodenoson
CAS No.	144348-08-3
Molecular Formula	C₁₉H₂₇N₇O₄
Molecular Weight	417.47 g/mol
Synonyms	Binodenoson; MRE-0470; WRC-0470; 2-[[(3R,4R,5S)-4-[6-Amino-2-(1-pentylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxy-2-oxido(oxo)-1,2-oxaphospholan-5-yl]oxy]ethanol; 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide derivative; Adenosine A2A Receptor Agonist WRC-0470; BINODENOSON (USAN); MRE 0470
EINECS	Contact for details

Quality Control

Our Binodenoson is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) are provided, detailing parameters such as assay, purity by HPLC, and identification. We adhere to cGMP principles where applicable to support our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.