Description

Acid Citrate Dextrose is a critical anticoagulant and preservative solution used primarily in blood banking and clinical diagnostics. Its precise formulation is essential for maintaining the viability and functionality of blood cells during storage and processing. This product is indispensable for manufacturers of blood collection tubes, medical device companies, and clinical laboratories globally, ensuring the safety and efficacy of blood-derived products.

Application

• Anticoagulant for Blood Collection: The primary application is as an additive in vacuum blood collection tubes (e.g., ACD tubes) to prevent coagulation by chelating calcium ions, preserving blood for various tests.
• Preservative Solution for Whole Blood and Red Cells: Used in specific formulations for the extended storage of whole blood and packed red blood cells, maintaining cellular integrity and function.
• Molecular Diagnostics and Genetic Testing: Serves as a stabilizing agent for white blood cells, preserving DNA and RNA for downstream PCR, sequencing, and other molecular biology applications.
• HLA Typing and Immunohematology: Essential in laboratories performing human leukocyte antigen (HLA) typing and other specialized blood group serology tests that require viable lymphocytes.
• Forensic Science: Employed as a preservative for blood samples collected for DNA analysis in forensic investigations.
• Cell Culture and Research: Used in specific research protocols as a component of media or solutions for isolating and processing primary cells from blood.
• Manufacturing of In-Vitro Diagnostic (IVD) Devices: A key raw material for companies producing pre-filled blood collection systems and diagnostic kits.

Basic Information

Product Name	Acid Citrate Dextrose
CAS No.	13838-07-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ACD Solution; Anticoagulant Citrate Dextrose Solution; Citrate Dextrose Solution; Acid-Citrate-Dextrose; ACD-A; ACD-B; Trisodium Citrate Dihydrate and Dextrose Solution; Anticoagulant Solution A
EINECS	Contact for details

Quality Control

Our Acid Citrate Dextrose is manufactured under strict quality management systems. Each batch is tested to ensure it meets stringent specifications for identity, purity, and performance, suitable for sensitive in-vitro diagnostic and medical device applications. Certificates of Analysis (COA) documenting compliance with relevant pharmacopoeial standards (e.g., USP, EP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container sealed to protect the hygroscopic components from moisture.

Specification

Item	Specification
Description	Clear, colorless to slightly yellow solution
Identification (IR)	Conforms
pH	4.5 - 5.5
Assay (Citrate by Titration)	22.0 - 24.5 g/L
Assay (Dextrose by HPLC)	24.0 - 26.0 g/L
Sterility Test	Sterile
Endotoxin	< 0.5 EU/mL
Particulate Matter	Meets requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.