Description

1-Methyl-7-Deazaguanine is a purine analog and a modified nucleobase of significant interest in biochemical research and pharmaceutical development. This compound serves as a versatile building block for the synthesis of nucleoside analogs and oligonucleotides with tailored properties. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, molecular biology, and antiviral/anticancer drug discovery to explore novel therapeutic mechanisms and diagnostic tools.

Application

• Medicinal Chemistry Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs for pharmaceutical research.
• Antiviral/Anticancer Agent Development: Used to create modified nucleic acid components that can interfere with viral replication or cancer cell proliferation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and repair pathways.
• Oligonucleotide Synthesis: Incorporated into synthetic DNA or RNA strands to study base-pairing properties, stability, and for diagnostic probe development.
• Academic & Industrial R&D: Serves as a fundamental research chemical in universities and corporate labs for exploring new chemical biology applications.

Basic Information

Product Name	1-Methyl-7-Deazaguanine
CAS No.	90065-66-0
Molecular Formula	C₇H₇N₅O
Molecular Weight	177.16 g/mol
Synonyms	7-Deaza-1-methylguanine; 1-Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 1-Methyl-7-azaguanine; 1-Methylguanine (7-deaza analog); Pyrrolo[2,3-d]pyrimidin-4-amine, 1-methyl-7H-; 1-Methyl-7-deazaguanosine aglycone
EINECS	Contact for details

Quality Control

Our 1-Methyl-7-Deazaguanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.