Description

((2R,3S,5R)-5-(5-(3-Aminopropyl)-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3-Hydroxytetrahydrofuran-2-Yl)Methyl Tetrahydrogen Triphosphate is a high-purity, chemically defined nucleotide analog with significant biological activity. This compound is critical for advanced research and development in life sciences, serving as a key building block or substrate in enzymatic studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on nucleotide metabolism, antiviral drug discovery, and molecular biology applications.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study kinases, polymerases, and other nucleotide-dependent enzymes.
• Antiviral Drug Discovery: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel nucleoside analog-based therapeutics.
• Molecular Biology: Employed in the study of DNA/RNA synthesis, repair mechanisms, and as a tool compound for probing nucleic acid interactions.
• Pharmaceutical Development: Acts as a critical raw material in the synthesis of potential prodrugs targeting viral infections and certain cancers.
• Diagnostic Reagent Manufacturing: Incorporated into specialized kits and reagents for molecular diagnostics and high-throughput screening platforms.

Basic Information

Item	Details
Product Name	((2R,3S,5R)-5-(5-(3-Aminopropyl)-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3-Hydroxytetrahydrofuran-2-Yl)Methyl Tetrahydrogen Triphosphate
CAS No.	90015-82-0
Molecular Formula	C13H23N4O15P3
Molecular Weight	568.27 g/mol
Synonyms	5'-Triphosphoryl-1-(3-aminopropyl)deoxyuridine; 1-(3-Aminopropyl)deoxyuridine 5'-triphosphate; dUrd(ap)TP; 5'-TP-1-(3-aminopropyl)-2'-deoxyuridine; 1-(3-Aminopropyl)-2'-deoxyuridine-5'-triphosphate; ((2R,3S,5R)-5-(5-(3-Aminopropyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen triphosphate; Nucleotide analog 90015-82-0
EINECS	Contact for details

Quality Control

Our ((2R,3S,5R)-5-(5-(3-Aminopropyl)-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3-Hydroxytetrahydrofuran-2-Yl)Methyl Tetrahydrogen Triphosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, it is recommended to store under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.