Description

Histoplasmin is a purified protein derivative (PPD) antigen derived from the fungus *Histoplasma capsulatum*. This biological reagent is essential for immunological testing and research, providing a standardized and reliable tool for detecting exposure to histoplasmosis. It is primarily utilized in clinical diagnostics, epidemiological studies, and immunological research within the pharmaceutical, biotechnology, and public health sectors.

Application

• Diagnostic Skin Testing: The primary application is for the intradermal skin test (Histoplasmin skin test) to determine delayed-type hypersensitivity and past exposure to *Histoplasma capsulatum*.
• Clinical Immunology: Used as a reference antigen in in-vitro assays, such as lymphocyte stimulation tests, to assess cell-mediated immune responses in patients.
• Epidemiological Research: Employed in population-based studies to map the prevalence and distribution of histoplasmosis in endemic regions.
• Vaccine Research & Development: Serves as a critical antigen in the research and development of immunotherapies and diagnostic vaccines for fungal diseases.
• Quality Control & Standardization: Acts as a standard reagent for the calibration and validation of other diagnostic kits and immunological reagents targeting histoplasmosis.

Basic Information

Product Name	Histoplasmin
CAS No.	9008-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Histoplasmin Antigen; Histoplasmin PPD; Histoplasmin Skin Test Antigen; Histoplasma Antigen; Histoplasma capsulatum Antigen; Histoplasmin Derivative; PPD-Histoplasmin
EINECS	Contact for details

Quality Control

Our Histoplasmin is manufactured under strict quality systems to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous testing for sterility, specificity, and potency. A comprehensive Certificate of Analysis (COA) is provided, detailing relevant specifications to support your research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. Do not freeze. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (Immunodiffusion)	Conforms
Protein Content	Contact for details
Potency (Skin Test)	Standardized
Sterility	Sterile
pH	6.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.