Description

Tributylsilane is a versatile organosilicon compound with the CAS number 998-41-4, widely used as a key reagent and intermediate in advanced chemical synthesis. Its primary value lies in its role as a selective reducing agent and a source of the tributylsilyl group for protection and functionalization in organic and organometallic chemistry. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors, where precise chemical transformations are critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) as a protecting group for alcohols and other functional groups.
• Selective Reducing Agent: Employed in organic synthesis for the selective reduction of specific functional groups, such as converting carbonyls to alcohols under mild conditions.
• Surface Modification: Acts as a precursor for creating hydrophobic coatings on glass, silica, and other metal oxides in material science applications.
• Cross-Coupling Reactions: Serves as a reagent in palladium-catalyzed cross-coupling reactions, such as the Hiyama coupling, for forming carbon-carbon bonds.
• Polymer Chemistry: Utilized as a chain transfer agent or modifying agent in the production of silicone-based polymers and resins.
• Laboratory Reagent: A valuable tool in research laboratories for method development and exploratory synthesis in organosilicon chemistry.

Basic Information

Item	Details
Product Name	Tributylsilane
CAS No.	998-41-4
Molecular Formula	C₁₂H₂₈Si
Molecular Weight	200.44 g/mol
Synonyms	Tributylsilane; Silane, tributyl-; Butylsilane; Tri-n-butylsilane; n-Tributylsilane; TBS-H; HSitBu₃; Tributylsilyl hydride
EINECS	213-632-1

Quality Control

Our Tributylsilane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy, to verify identity and assay. A Certificate of Analysis (COA) detailing purity and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	0.78 - 0.82 g/mL
Refractive Index (n20D)	1.430 - 1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.