Description

Benzohexonium is a quaternary ammonium compound with ganglionic blocking activity, primarily used as a research chemical and pharmaceutical intermediate. Its significance lies in its role as a classic nicotinic acetylcholine receptor (nAChR) antagonist, making it a valuable tool for neurological and pharmacological studies. This product is essential for researchers in pharmaceutical development, academic institutions, and contract research organizations (CROs) investigating autonomic nervous system function and receptor mechanisms.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of ganglionic blockade and nicotinic acetylcholine receptor (nAChR) antagonism.
• Neuroscience Studies: Employed in vitro and in vivo to investigate autonomic nervous system transmission and the effects of ganglionic blockers.
• Pharmaceutical Intermediate: Serves as a key synthetic building block in the development of novel therapeutic agents targeting the cholinergic system.
• Biochemical Assay Development: Utilized in the development and validation of high-throughput screening (HTS) assays for receptor activity.
• Academic & Educational Use: A standard compound for teaching and demonstrating principles of neuropharmacology and autonomic pharmacology in university laboratories.

Basic Information

Product Name	Benzohexonium
CAS No.	971-60-8
Molecular Formula	C₂₈H₄₂N₂O₄
Molecular Weight	470.65 g/mol
Synonyms	Benzohexonium; Benzohexonium Iodide (salt form); Hexonium B; Hexamethonium Benzoate Derivative; 1,6-Hexanediylbis[(methylphenylmethyl)dimethylammonium] dibenzoate; N,N'-Dimethyl-N,N'-diphenethyl-1,6-hexanediaminium dibenzoate
EINECS	Contact for details

Quality Control

Our Benzohexonium is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support research and development with material suitable for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.