Description

2'-Deoxyuridine 5'-Monophosphate is a critical nucleotide monophosphate essential for research in molecular biology and biochemistry. This compound serves as a fundamental building block and a key intermediate in the study of DNA synthesis, repair mechanisms, and enzymatic pathways. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on nucleoside metabolism, antiviral drug development, and cancer research.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly for thymidylate synthase and other nucleotide-metabolizing enzymes.
• Pharmaceutical Development: Serves as a key precursor or reference standard in the synthesis and screening of antiviral and anticancer nucleoside analogs.
• Diagnostic Reagent Manufacturing: Incorporated into kits for molecular diagnostics, PCR, and other nucleic acid amplification techniques.
• Cell Culture & Metabolism Studies: Employed in research investigating nucleotide salvage pathways and cellular proliferation mechanisms.
• Enzyme Inhibition Assays: Acts as a standard or competitor in assays designed to discover and characterize novel enzyme inhibitors.

Basic Information

Product Name	2'-Deoxyuridine 5'-Monophosphate
CAS No.	964-26-1
Molecular Formula	C9H13N2O8P
Molecular Weight	308.18 g/mol
Synonyms	dUMP; Deoxyuridylic Acid; 2'-Deoxyuridine 5'-(Dihydrogen Phosphate); 5'-dUMP; Uridine, 2'-deoxy-, 5'-(dihydrogen phosphate); Deoxyuridine Monophosphate; 2'-Deoxy-5'-uridylic Acid
EINECS	213-518-4

Quality Control

Our 2'-Deoxyuridine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); prolonged exposure to air, moisture, or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Test in water: Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.