Description

2'-Deoxyadenosine is a fundamental nucleoside building block essential for DNA synthesis and biochemical research. Its high purity and stability are critical for applications demanding precise molecular control and reproducible results. This compound is primarily utilized by the pharmaceutical, biotechnology, and life science research industries for applications ranging from oligonucleotide synthesis to enzymatic studies.

Application

• Oligonucleotide and DNA Synthesis: A key raw material (phosphoramidite) for solid-phase synthesis of primers, probes, and gene fragments.
• Biochemical Research: Substrate for studies involving DNA polymerases, kinases, and other nucleic acid-metabolizing enzymes.
• Pharmaceutical Intermediates: Serves as a precursor in the development of antiviral and anticancer nucleoside analog drugs.
• Cell Culture & Microbiology: Used in defined media for studying nucleotide metabolism and cell proliferation.
• Diagnostic Reagent Manufacturing: Incorporated into kits for PCR, sequencing, and other molecular diagnostics.
• Standards & Calibrants: High-purity grade used as a reference standard in analytical laboratories for quality control.

Basic Information

Product Name	2'-Deoxyadenosine
CAS No.	958-09-8
Molecular Formula	C10H13N5O3
Molecular Weight	251.24 g/mol
Synonyms	2'-Deoxyadenosine; Deoxyadenosine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine; Adenine deoxyriboside; dA; 2'-dA; Deoxyriboadenosine; NSC 83256
EINECS	213-500-0

Quality Control

Our 2'-Deoxyadenosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and tests for related substances and residual solvents. A Certificate of Analysis (COA) is supplied with each batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Solvent Residues (GC)	Complies with ICH guidelines
Specific Rotation	-25° to -30° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.