Description

2'-Deoxyuridine is a pyrimidine deoxyribonucleoside, a fundamental building block in nucleic acid research and synthesis. This compound is a critical intermediate in the development of antiviral and anticancer agents, particularly in the synthesis of nucleoside analogs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity biochemical precursors for drug discovery and molecular biology applications.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of antiviral drugs (e.g., Idoxuridine, Trifluridine) and chemotherapeutic agents.
• Biochemical Research: Used as a substrate in enzymatic studies, DNA repair research, and as a standard in analytical chromatography.
• Molecular Biology: Essential component in the study of thymidylate synthase inhibition and nucleotide metabolism pathways.
• Diagnostic Reagent Manufacturing: Employed in the production of kits and reagents for genetic testing and cellular assays.
• Antiviral Agent Development: Serves as a core structure for modifying nucleoside analogs to target viral polymerases.
• Academic & Industrial R&D: Utilized in universities and corporate labs for fundamental life science research and new drug candidate screening.

Basic Information

Product Name	2'-Deoxyuridine
CAS No.	951-78-0
Molecular Formula	C9H12N2O5
Molecular Weight	228.20 g/mol
Synonyms	Deoxyuridine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil; Uracil deoxyriboside; 2′-dUrd; dU; NSC 73686; DU
EINECS	213-449-5

Quality Control

Our 2'-Deoxyuridine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.