Description

trans-2-Phenyl-1-Cyclopropanecarbonyl Chloride CAS NO 939-87-7 is a high-purity, reactive organic intermediate featuring a cyclopropane ring and an acid chloride functional group. This compound is valued for its unique structural motif, which is integral to synthesizing molecules with enhanced biological activity and specific stereochemistry. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and complex chiral molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a rigid cyclopropane scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the phenylcyclopropane structure confers specific biological properties.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Useful for modifying peptides or other biomolecules to study protein interactions and biological pathways.

Basic Information

Product Name	trans-2-Phenyl-1-Cyclopropanecarbonyl Chloride
CAS No.	939-87-7
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	(1R,2S)-rel-2-Phenylcyclopropanecarbonyl Chloride; trans-2-Phenylcyclopropanecarboxylic Acid Chloride; (1R,2S)-2-Phenylcyclopropanecarbonyl Chloride; (1R,2S)-2-Phenylcyclopropanecarboxylic Acid Chloride; 2-Phenylcyclopropanecarbonyl Chloride, trans-; Cyclopropanecarbonyl chloride, 2-phenyl-, trans-; (1S,2R)-2-Phenylcyclopropanecarbonyl Chloride
EINECS	213-363-6

Quality Control

Our trans-2-Phenyl-1-Cyclopropanecarbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.