Description

o-Toluoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in organic synthesis. Its primary value lies in its ability to efficiently introduce the o-toluoyl moiety, enabling the production of a wide range of advanced intermediates. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring benzamide or related structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where it acts as an acylating agent to create novel amide-based molecules.
• Dye and Pigment Manufacturing: Employed in the synthesis of organic dyes, pigments, and optical brighteners, contributing to color fastness and specific chromophoric properties.
• Polymer Chemistry: Serves as a monomer or modifier in the production of specialty polymers, including polyamides and polyimides, to alter thermal or mechanical properties.
• Organic Synthesis & Research: A fundamental tool in academic and industrial laboratories for peptide coupling, Friedel-Crafts acylation, and the preparation of ketones and esters.
• Perfume and Flavor Industry: Utilized in the controlled synthesis of specific aromatic esters that contribute to complex fragrance and flavor profiles.

Basic Information

Item	Detail
Product Name	o-Toluoyl Chloride
CAS No.	933-88-0
Molecular Formula	C8H7ClO
Molecular Weight	154.59 g/mol
Synonyms	2-Methylbenzoyl chloride; o-Methylbenzoyl chloride; 2-Toluoyl chloride; ortho-Toluoyl chloride; (2-Methylphenyl)carbonyl chloride; α-Toluoyl chloride; o-Toluyoyl chloride; Benzoyl chloride, 2-methyl-
EINECS	213-277-8

Quality Control

Our o-Toluoyl Chloride is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including assay, identity confirmation, and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting purity, physical properties, and safety data are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (as HCl)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.