Description

7-Ketodeoxycholic Acid is a key oxidized derivative of the primary bile acid deoxycholic acid. This compound serves as a critical intermediate and reference standard in pharmaceutical research and development, particularly in the study of bile acid metabolism and synthesis. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity biochemicals for analytical and synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel therapeutic agents and more complex bile acid derivatives.
• Biochemical Research: Used as a reference standard and metabolic probe in studies of liver function, cholesterol metabolism, and gastrointestinal biology.
• Analytical Chemistry: Serves as a high-purity standard for HPLC, LC-MS, and other analytical methods to quantify bile acids in biological samples.
• Enzymology Studies: Employed as a substrate or inhibitor to study the activity of enzymes involved in steroid and bile acid transformation.
• Fine Chemical Synthesis: A starting material for the preparation of specialized surfactants, chiral resolving agents, and other value-added chemicals.

Basic Information

Product Name	7-Ketodeoxycholic Acid
CAS No.	911-40-0
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	7-Oxodeoxycholic Acid; 3α,12α-Dihydroxy-7-oxo-5β-cholan-24-oic Acid; 7-Keto-DCA; 7-KDCA; 7-Oxo-DCA; Deoxycholic Acid 7-one; 7-Oxolithocholic Acid
EINECS	Contact for details

Quality Control

Our 7-Ketodeoxycholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.