Description

2'-Deoxyguanosine 5'-Monophosphate is a fundamental nucleotide monophosphate, serving as a critical building block for DNA synthesis and repair. Its high purity and reliable quality are essential for ensuring the accuracy and reproducibility of downstream biochemical processes and molecular biology applications. This compound is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and diagnostic sectors for applications ranging from oligonucleotide synthesis to biochemical research.

Application

• Oligonucleotide Synthesis: A key raw material (dGMP) in the solid-phase synthesis of DNA strands for PCR primers, probes, and gene fragments.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and nucleotide metabolism research.
• Pharmaceutical Intermediates: Serves as a critical starting material or intermediate in the development of antiviral drugs and nucleotide-based therapeutics.
• Diagnostic Reagent Production: Incorporated into the manufacture of diagnostic kits and reagents for genetic testing and molecular diagnostics.
• Cell Culture & Media Supplements: Used in specialized cell culture media formulations to support the growth of certain fastidious cell lines.
• Enzyme Cofactor Studies: Employed in research investigating the mechanisms of DNA polymerases, kinases, and other nucleic acid-processing enzymes.

Basic Information

Product Name	2'-Deoxyguanosine 5'-Monophosphate
CAS No.	902-04-5
Molecular Formula	C10H14N5O7P
Molecular Weight	347.22 g/mol
Synonyms	Deoxyguanylic acid; dGMP; 2'-Deoxy-GMP; Deoxyguanosine monophosphate; 2'-Deoxyguanosine 5'-(dihydrogen phosphate); Guanine deoxyriboside monophosphate; 5'-dGMP
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine 5'-Monophosphate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and production use. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
pH (1% Solution)	2.0 - 4.0
Related Substances (HPLC)	Individual impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.