Description

Guaifenesin CAS NO 93-14-1 is an expectorant agent widely recognized for its mucolytic properties, helping to loosen and thin mucus in the airways. This high-purity pharmaceutical intermediate is critical for ensuring the efficacy and safety of finished cough and cold formulations. It is an essential raw material for manufacturers in the pharmaceutical, nutraceutical, and over-the-counter (OTC) medication sectors seeking reliable, compliant supply for respiratory health products.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key expectorant in prescription and OTC cough syrups, tablets, and liquid capsules.
• Combination Drug Formulations: Used in multi-symptom relief products combined with antihistamines, decongestants, and analgesics.
• Veterinary Pharmaceuticals: Incorporated into expectorant formulations for respiratory conditions in animals.
• Nutraceutical Supplements: Found in dietary supplements aimed at supporting respiratory health and mucus clearance.
• Lozenges and Throat Sprays: A component in soothing throat care products designed to relieve coughs.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for new respiratory therapies.

Basic Information

Product Name	Guaifenesin
CAS No.	93-14-1
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	Glyceryl guaiacolate; 3-(2-Methoxyphenoxy)-1,2-propanediol; Guaiacol glyceryl ether; Guaiphenesin; Resyl; My 301; Geeslin; Gecolate; Robitussin (brand name ingredient); Guaiamar
EINECS	202-222-5

Quality Control

Our Guaifenesin is manufactured under strict quality management systems, with specifications designed to meet or exceed major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling. Certificates of Analysis (COA) documenting purity, heavy metals, residual solvents, and related substances are available upon request to ensure full traceability and compliance for your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.