Description

Ambroxol CAS NO 18683-91-5 is a potent mucolytic agent and active pharmaceutical ingredient (API) derived from vasicine. It is a key therapeutic compound valued for its ability to effectively break down and clear mucus from the respiratory tract, improving bronchial clearance. This makes it an essential raw material for pharmaceutical manufacturers developing cough syrups, lozenges, tablets, and other formulations aimed at treating acute and chronic respiratory conditions such as bronchitis and asthma.

Application

• Pharmaceutical API: Primary active ingredient in prescription and over-the-counter (OTC) mucolytic and expectorant medications.
• Cough Syrup Production: Formulated into liquid oral solutions and suspensions for effective mucus clearance.
• Tablet & Lozenge Manufacturing: Used in solid oral dosage forms for convenient and controlled delivery.
• Pediatric Formulations: Incorporated into specially designed, lower-dose medications for children.
• Veterinary Pharmaceuticals: Applied in respiratory treatments for animals.
• Combination Drug Therapies: Used alongside antibiotics, antihistamines, or other APIs in multi-symptom relief products.
• Research & Development: Serves as a reference standard and starting material for novel drug development in respiratory therapy.

Basic Information

Product Name	Ambroxol
CAS No.	18683-91-5
Molecular Formula	C13H18Br2N2O
Molecular Weight	378.10 g/mol
Synonyms	trans-4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol; Ambroxol Hydrochloride (salt form); NA-872; Mucosolvan; Lasolvan; Surbronc; Ambril; Ventilate; Mucoclear
EINECS	242-457-2

Quality Control

Our Ambroxol is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.