Description

Eprazinone Dihydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial importance. This compound is valued for its critical role in the synthesis of advanced therapeutic agents, particularly in respiratory medicine. It is essential for manufacturers and research institutions engaged in the development and production of specialized pharmaceuticals, requiring a reliable and consistent supply of high-quality raw materials.

Application

• Pharmaceutical API Synthesis: Primary use as an active ingredient or key intermediate in the manufacture of prescription medications.
• Respiratory Therapeutics: Core component in the production of mucolytic and expectorant drugs for treating bronchial conditions.
• Research & Development: Serves as a critical reference standard and building block in pharmacological and medicinal chemistry research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant drug production.
• Analytical Standard: Used in quality control laboratories for HPLC, LC-MS, and other analytical method development and validation.
• Preclinical Studies: Utilized in the formulation of dosage forms for animal studies and toxicological evaluations.

Basic Information

Product Name	Eprazinone Dihydrochloride
CAS No.	10402-53-6
Molecular Formula	C₂₄H₃₂N₂O₂·2HCl
Molecular Weight	461.44 g/mol
Synonyms	Eprazinone HCl; E-671; 1-(2-Phenylethyl)-4-(2-(3-methoxyphenyl)ethyl)piperazine Dihydrochloride; 4-[2-(3-Methoxyphenyl)ethyl]-1-(2-phenylethyl)piperazine Dihydrochloride; Mepramidil Dihydrochloride; Respilene; Mucomyst (as derivative); Mucolytic agent E-671
EINECS	Contact for details

Quality Control

Our Eprazinone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, supporting compliance with cGMP and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.