Description

n-Acetyl-Cysteine (NAC) is a modified amino acid derivative of L-cysteine, valued for its role as a potent antioxidant and mucolytic agent. Its primary commercial significance lies in its ability to act as a precursor to glutathione, a critical intracellular antioxidant, making it essential for applications demanding oxidative stress management. This compound is a key raw material for the pharmaceutical, nutraceutical, and research industries, where high-purity standards are paramount for efficacy and safety.

Application

• Pharmaceutical Ingredient: Used as an active pharmaceutical ingredient (API) in mucolytic drugs for respiratory conditions like chronic bronchitis and COPD, and as an antidote for acetaminophen (paracetamol) overdose.
• Dietary Supplements & Nutraceuticals: Incorporated into capsules, tablets, and powders for its antioxidant properties, supporting liver health, immune function, and detoxification pathways.
• Cell Culture & Biochemical Research: Employed in laboratory settings as a reducing agent to prevent oxidation in cell culture media and as a tool compound in studies of oxidative stress and apoptosis.
• Cosmeceuticals: Formulated into skincare products for its antioxidant and anti-aging benefits, helping to protect skin from environmental damage.
• Veterinary Medicine: Used in veterinary pharmaceuticals for similar therapeutic applications as in human medicine, including respiratory support and hepatoprotection.
• Food & Beverage (as a permitted food additive in some regions): Functions as a dough conditioner and antioxidant in food processing, though applications are grade-specific and subject to regional regulations.

Basic Information

Product Name	n-Acetyl-Cysteine
CAS No.	18829-79-3
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	N-Acetylcysteine; NAC; N-Acetyl-L-cysteine; Acetylcysteine; L-α-Acetamido-β-mercaptopropionic acid; Mercapturic acid; Airbron; Fluimucil; Mucomyst; ACC
EINECS	242-638-2

Quality Control

We supply n-Acetyl-Cysteine in various grades, including Pharmaceutical (USP/EP), Food (FCC), and high-purity Reagent grades. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Quality management systems are in place to support GMP, ISO, and REACH compliance for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 101.0%
Specific Rotation	+21.0° to +27.0°
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.