Description

Calcium Guaiacolsulfonate is an organosulfur compound derived from guaiacol, valued for its expectorant and mucolytic properties. This makes it a critical active pharmaceutical ingredient (API) and intermediate in the formulation of respiratory medications. It is primarily sought by manufacturers in the pharmaceutical, veterinary, and nutraceutical industries for producing cough syrups, lozenges, and other therapeutic agents aimed at relieving bronchial congestion.

Application

• Pharmaceutical API: Core ingredient in prescription and over-the-counter (OTC) expectorant and cough suppressant formulations.
• Veterinary Medicine: Used in animal health products for treating respiratory conditions in livestock and companion animals.
• Nutraceutical Supplements: Incorporated into dietary supplements designed to support respiratory health and clear airways.
• Syrup and Liquid Preparations: A key component in the production of stable, palatable oral liquid medications.
• Lozenges and Troches: Utilized in solid dosage forms for slow release and localized action in the throat.
• Chemical Synthesis: Serves as a valuable sulfonated intermediate for further organic synthesis in fine chemical production.

Basic Information

Product Name	Calcium Guaiacolsulfonate
CAS No.	17139-96-7
Molecular Formula	C14H14CaO10S2
Molecular Weight	446.46 g/mol
Synonyms	Calcium Guaiacolsulfonate; Calcium Guaiacolsulphonate; Guaiacolsulfonic Acid Calcium Salt; Guaiacolsulphonic Acid Calcium Salt; Calcium 2-Methoxyphenol-4-sulfonate; Expectorant Calcium Salt; Thiocol Calcium; CAS 17139-96-7
EINECS	241-212-9

Quality Control

Our Calcium Guaiacolsulfonate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with compliance to relevant pharmacopoeial guidelines (e.g., USP, EP) where specified. A comprehensive Certificate of Analysis (COA), detailing identity, assay, purity, and impurity profiles, is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbiological Control	Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.