Description

Erdosteine CAS NO 105426-14-0 is a synthetic mucolytic agent and antioxidant belonging to the thiol derivative class. It is a critical active pharmaceutical ingredient (API) valued for its ability to reduce the viscosity of mucus and protect lung tissue from oxidative damage. This compound is essential for manufacturers in the global pharmaceutical industry developing treatments for chronic respiratory conditions such as chronic obstructive pulmonary disease (COPD) and bronchitis.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription mucolytic and antioxidant medications.
• Respiratory Therapeutics: Formulated into tablets, capsules, and granules for the treatment of acute and chronic bronchopulmonary diseases.
• COPD Management: A key component in therapeutic regimens aimed at reducing exacerbations and improving lung function in COPD patients.
• Otitis Media Adjunct Therapy: Used in some formulations to help manage mucus-related complications in middle ear infections.
• Research & Development: Serves as a reference standard and building block in pharmacological research for new respiratory and anti-inflammatory drugs.
• Veterinary Pharmaceuticals: Applied in veterinary medicine for treating respiratory conditions in animals.

Basic Information

Item	Details
Product Name	Erdosteine
CAS No.	105426-14-0
Molecular Formula	C8H11NO4S2
Molecular Weight	249.31 g/mol
Synonyms	Erdosteine; (R,S)-2-[(Carboxymethyl)thio]-N-(2,2-dimethyl-1,3-thiazolidin-4-yl)ethanamide; (RS)-2-[(Carboxymethyl)thio]-N-(tetrahydro-2,2-dimethyl-4-thiazolyl)acetamide; N-[2-Oxo-2-[(tetrahydro-2,2-dimethyl-4-thiazolyl)amino]ethyl]homocysteine thiolactone; Erdosteinum; Flustat; Erdomed; Vectrine; Dithiosteine
EINECS	Contact for details

Quality Control

Our Erdosteine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity pharmacopeial standards, including identification, assay, and control of specified impurities. Certificates of Analysis (COA) documenting compliance with in-house specifications are available for every shipment. We support customer audits and can provide materials for qualification against USP, EP, or other relevant monographs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Specific Optical Rotation	-0.10° to +0.10° (c=1 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.