Description

2-Hydroxy-2'-Deoxy-2'-Fluoro-β-D-Arabino Adenosine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or reference standard for the development of novel antiviral and anticancer therapeutics. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on nucleoside chemistry, medicinal chemistry, and the synthesis of modified nucleic acids.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorine and hydroxyl modifications on nucleoside activity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair mechanisms.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Nucleoside Chemistry: A valuable reagent for the synthesis of more complex oligonucleotides or nucleotide prodrugs.
• Antiviral Agent Development: Investigated for potential activity against a range of viral targets due to its modified sugar moiety.

Basic Information

Product Name	2-Hydroxy-2'-Deoxy-2'-Fluoro-β-D-Arabino Adenosine
CAS No.	899827-82-8
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	2'-Deoxy-2'-fluoro-β-D-arabinofuranosyladenine; 2'-F-β-D-AraA; 2'-F-AraA; 2'-Fluoro-2'-deoxy-β-D-arabinoadenosine; 2'-Fluoro-arabinofuranosyladenine; 9-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-amine; 2'-F-β-D-Arabinofuranosyladenine; 2'-Fluoro-β-D-arabinoadenosine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2'-Deoxy-2'-Fluoro-β-D-Arabino Adenosine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.