Description

2',3'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is a high-value fluorinated organic intermediate featuring a protected carbonyl group. This compound is critical for synthetic chemists requiring precise molecular architecture in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorine atoms and ketone moiety enhance biological activity and stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require specific fluorine-containing aromatic units.
• Organic Synthesis: The acetal-protected carbonyl group makes it a versatile reagent for multi-step syntheses where selective deprotection is needed.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2',3'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone
CAS No.	898786-79-3
Molecular Formula	C₁₆H₂₀F₂O₃
Molecular Weight	298.33 g/mol
Synonyms	4-(5,5-Dimethyl-1,3-dioxan-2-yl)-2',3'-difluorobutyrophenone; 2',3'-Difluoro-4-(5,5-dimethyl-1,3-dioxan-2-yl)-1-butanone; 1-[2,3-Difluorophenyl]-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one; 2,3-Difluoro-ω-(5,5-dimethyl-1,3-dioxan-2-yl)acetophenone; DFDB Intermediate; DFDK Acetal
EINECS	Contact for details

Quality Control

Our 2',3'-Difluoro-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.