Description

3-(1,3-Thiazol-2-Yl)Benzoyl Chloride is a high-purity, reactive benzoyl chloride derivative featuring a thiazole heterocycle, making it a valuable building block for advanced organic synthesis. This compound is critical for introducing the 3-(thiazol-2-yl)benzoyl moiety into target molecules, enabling the development of novel chemical entities with specific functionalities. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring heterocyclic scaffolds.
• Agrochemical Research: Used in the synthesis of advanced herbicide and fungicide candidates, leveraging the bioactivity of the thiazole ring.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules to create tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-(1,3-Thiazol-2-Yl)Benzoyl Chloride
CAS No.	898288-99-8
Molecular Formula	C12H8ClNOS
Molecular Weight	249.71 g/mol
Synonyms	3-(Thiazol-2-yl)benzoyl chloride; 2-(3-Chlorocarbonylphenyl)thiazole; m-(2-Thiazolyl)benzoyl chloride; Benzoyl chloride, 3-(2-thiazolyl)-; 898288-99-8; 3-(1,3-Thiazol-2-yl)benzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-(1,3-Thiazol-2-Yl)Benzoyl Chloride is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.