Description

Imiquimod Maleate is a pharmaceutical-grade active pharmaceutical ingredient (API) and a key derivative of the immunomodulatory agent Imiquimod. This compound is of significant commercial interest for its role in the development and manufacturing of advanced topical treatments. It is primarily required by pharmaceutical companies and research institutions engaged in dermatological and oncological therapeutic development.

Application

• Pharmaceutical API: Primary use as the active ingredient in topical cream formulations for treating actinic keratosis, superficial basal cell carcinoma, and external genital warts.
• Immunomodulatory Research: A critical tool in preclinical and clinical research for studying toll-like receptor 7 (TLR7) agonists and their effects on the immune system.
• Dermatological Drug Development: Serves as a reference standard and a key intermediate in the synthesis of novel dermatological drugs targeting viral infections and pre-cancerous skin lesions.
• Veterinary Medicine: Investigated for use in topical treatments for certain skin conditions in animals.
• Cosmeceutical Research: Explored in high-end research for potential applications in targeted skin rejuvenation and repair formulations.

Basic Information

Product Name	Imiquimod (Maleate)
CAS No.	896106-16-4
Molecular Formula	C₁₄H₁₆N₄ • C₄H₄O₄
Molecular Weight	390.38 g/mol
Synonyms	1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine maleate; Imiquimod hydrogen maleate; R-837 maleate; Aldara (brand name) API derivative; S-26308 maleate; 4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline maleate salt
EINECS	Contact for details

Quality Control

Our Imiquimod Maleate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, related substances, residual solvents, and identification. We adhere to cGMP principles where applicable to ensure supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time conforms to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.