Description

1-[(4-Isothiocyanatophenyl)Sulfonyl]Indoline is a specialized organic building block featuring both a sulfonyl and an isothiocyanate functional group, enabling its use as a key intermediate in advanced chemical synthesis. This compound is valued for its role in creating complex molecular architectures, particularly in the development of novel bioactive compounds and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, especially for targeted therapies.
• Bioconjugation Reagent: The reactive isothiocyanate group allows for covalent attachment to amines in proteins, peptides, or other biomolecules for labeling and probe development.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialized polymers with tailored properties.
• Chemical Biology Tool: Employed in probe synthesis for studying enzyme activity or protein function within biological systems.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex chromophores for high-performance dyes.

Basic Information

Product Name	1-[(4-Isothiocyanatophenyl)Sulfonyl]Indoline
CAS No.	895935-43-0
Molecular Formula	C15H10N2O2S2
Molecular Weight	314.38 g/mol
Synonyms	1-[(4-Isothiocyanatophenyl)sulfonyl]-2,3-dihydro-1H-indole; 4-(Indoline-1-sulfonyl)phenyl isothiocyanate; 1H-Indole, 2,3-dihydro-1-[(4-isothiocyanatophenyl)sulfonyl]-; N-(4-Isothiocyanatophenylsulfonyl)indoline; 1-(4-Isothiocyanatobenzene-1-sulfonyl)indoline
EINECS	Contact for details

Quality Control

Our production of 1-[(4-Isothiocyanatophenyl)Sulfonyl]Indoline adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.