Description

1-Azido-2-Fluoroethane is a specialized bifunctional organic compound that serves as a valuable building block in advanced chemical synthesis. Its unique structure, combining an azide group with a fluorine atom on a short ethane backbone, makes it a critical reagent for introducing both fluorinated and azido functionalities into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from medicinal chemistry to polymer modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly for incorporating fluorine atoms to modulate metabolic stability and bioavailability.
• Click Chemistry Reagent: Serves as a key component in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Agrochemical Synthesis: Employed in the development of advanced pesticides and herbicides where the fluorine moiety enhances biological activity.
• Fluorinated Polymer Production: Acts as a monomer or modifier to introduce azide groups into polymer chains for subsequent cross-linking or labeling.
• Radiochemistry & Imaging Probes: Utilized in the preparation of fluorinated tracers and probes for Positron Emission Tomography (PET) and other imaging techniques.
• Energetic Materials Research: Investigated as a precursor in the development of specialized energetic compounds and propellants.

Basic Information

Product Name	1-Azido-2-Fluoroethane
CAS No.	894792-94-0
Molecular Formula	C2H4FN3
Molecular Weight	89.07 g/mol
Synonyms	2-Fluoroethyl azide; Azidofluoroethane; Fluoroazidoethane; 2-Fluoro-1-azidoethane; 1-Fluoro-2-azidoethane; F-AEE; N3CH2CH2F
EINECS	Contact for details

Quality Control

Our 1-Azido-2-Fluoroethane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including NMR (¹H, ¹³C, ¹⁹F), IR spectroscopy, and GC-MS/HPLC analysis to verify chemical identity and purity. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat, sparks, and open flame. Due to its highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended storage temperature is 2-8°C for extended stability. Isolate from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.