Description

4-Quinazolinamine, n-(5-Chloro-1,3-Benzodioxol-4-Yl)-7-[2-(4-Methyl-1-Piperazinyl)Ethoxy]-5-[(Tetrahydro-2H-Pyran-4-Yl)Oxy]-, (2E)-2-Butenedioate (1:2) is a high-purity, complex organic salt with a defined molecular structure. This compound is of significant interest for its potential as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) in advanced research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Biochemical Research: Used as a reference standard or a tool compound in pharmacological studies and target validation.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and their biological activities.
• Custom Synthesis: Acts as a starting material for the contract manufacturing of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	4-Quinazolinamine, n-(5-Chloro-1,3-Benzodioxol-4-Yl)-7-[2-(4-Methyl-1-Piperazinyl)Ethoxy]-5-[(Tetrahydro-2H-Pyran-4-Yl)Oxy]-, (2E)-2-Butenedioate (1:2)
CAS No.	893428-72-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-[(oxan-4-yl)oxy]quinazolin-4-amine fumarate (2:1); (2E)-But-2-enedioic acid;2-[4-[(5-chloro-1,3-benzodioxol-4-yl)amino]-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-2-yl]hydrazinylidene]acetic acid; 893428-72-3; UNII-8VU54V8N1F; 8VU54V8N1F; Fumarate salt of a quinazolinamine derivative
EINECS	Contact for details

Quality Control

Our 4-Quinazolinamine derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.