Description

3'-Azido-3'-Deoxy-N6-Methyladenosine is a chemically modified nucleoside analog, a key building block in medicinal chemistry and biochemical research. This compound is valued for its role as a versatile intermediate in the synthesis of novel antiviral agents and for its utility in click chemistry applications. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and probe development.

Application

• Antiviral Drug Discovery: Serves as a critical synthetic intermediate for the development of nucleoside-based antiviral therapeutics.
• Bioconjugation & Click Chemistry: The azido group enables efficient, site-specific labeling of biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Biochemical Probe Synthesis: Used to create probes for studying enzyme mechanisms, nucleic acid interactions, and cellular processes.
• Medicinal Chemistry Research: Acts as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Nucleoside Analogue Library Construction: A fundamental component for generating diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	3'-Azido-3'-Deoxy-N6-Methyladenosine
CAS No.	889126-08-3
Molecular Formula	C11H14N8O3
Molecular Weight	306.28 g/mol
Synonyms	3'-Azido-3'-deoxy-N6-methyladenosine; 3'-Azido-N6-methyl-3'-deoxyadenosine; 1-(3-Azido-3-deoxy-β-D-ribofuranosyl)-N6-methyladenine; N6-Methyl-3'-azido-3'-deoxyadenosine; 3'-N3-N6-Me-Ado; 3'-Azido-N6-methyladenosine; 3'-Azido-3'-deoxy-N(6)-methyladenosine
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxy-N6-Methyladenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.