Description

4-Chloro-3-Hydroxybenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive acyl chloride group and a phenolic hydroxyl, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical resistance properties.
• Liquid Crystal & OLED Materials: A precursor in the synthesis of complex organic molecules for electronic display and lighting applications.
• Dyestuff & Pigment Manufacturing: Employed in the synthesis of high-performance, color-fast dyes and organic pigments.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-Chloro-3-Hydroxybenzoyl Chloride
CAS No.	888731-75-7
Molecular Formula	C7H4Cl2O2
Molecular Weight	191.01 g/mol
Synonyms	3-Hydroxy-4-chlorobenzoyl chloride; 4-Chloro-3-hydroxybenzoic acid chloride; 4-Chloro-3-hydroxybenzoyl chloride; 2-Chloro-5-(chlorocarbonyl)phenol; 5-Chloro-2-hydroxybenzoyl chloride; Benzoic acid, 4-chloro-3-hydroxy-, chloride; (4-Chloro-3-hydroxyphenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-Hydroxybenzoyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.