Description

[6-(3-Fluorophenyl)Pyridin-3-Yl]Methanol CAS NO 887974-66-5 is a high-value fluorinated pyridine derivative, serving as a critical building block in modern organic synthesis. Its core value lies in its unique molecular architecture, which combines a fluorinated aromatic ring with a pyridine-methanol functional group, enabling precise modifications for advanced material and pharmaceutical development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into novel active molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the creation of fluorinated liquid crystals, organic semiconductors, and advanced polymers with tailored electronic properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocyclic scaffolds.

Basic Information

Product Name	[6-(3-Fluorophenyl)Pyridin-3-Yl]Methanol
CAS No.	887974-66-5
Molecular Formula	C12H10FNO
Molecular Weight	203.21 g/mol
Synonyms	(6-(3-Fluorophenyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 6-(3-fluorophenyl)-; 6-(3-Fluorophenyl)-3-pyridinemethanol; 6-(3-Fluorophenyl)nicotinyl alcohol; 6-(m-Fluorophenyl)-3-pyridylmethanol; [6-(3-Fluorophenyl)-3-pyridyl]methanol; 3-Hydroxymethyl-6-(3-fluorophenyl)pyridine
EINECS	Contact for details

Quality Control

Our [6-(3-Fluorophenyl)Pyridin-3-Yl]Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.