Description

(5-Bromo-2,3-Difluorophenyl)Methanol is a high-purity, multi-functional aromatic building block featuring bromine and fluorine substituents on a benzyl alcohol core. This compound is valued for its role as a critical intermediate in advanced organic synthesis, enabling the introduction of complex, halogenated motifs into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to construct complex biaryl systems.
• Functional Polymer Monomer: Can be incorporated into polymer backbones or used to modify polymer side chains to impart specific properties like altered solubility or reactivity.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Product Name	(5-Bromo-2,3-Difluorophenyl)Methanol
CAS No.	887585-71-9
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	5-Bromo-2,3-difluorobenzyl alcohol; (5-Bromo-2,3-difluorophenyl)methanol; 2,3-Difluoro-5-bromobenzyl alcohol; 1-(5-Bromo-2,3-difluorophenyl)methanol; Benzenemethanol, 5-bromo-2,3-difluoro-; α-Hydroxymethyl-5-bromo-2,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our (5-Bromo-2,3-Difluorophenyl)Methanol is produced and tested under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.