Description

3-Bromo-5-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both the bromo-fluorophenyl moiety and the reactive acyl chloride group into target molecules in a single step. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the halogenated aromatic structure for bioactivity.
• Ligand and Material Science: Building block for creating specialized ligands for catalysis and monomers for high-performance polymers.
• Peptide Mimetics & Conjugation: Employed in the acylation reactions to modify peptides or create peptide-drug conjugates.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex halogenated organic dyes and pigments.

Basic Information

Product Name	3-Bromo-5-Fluorobenzoyl Chloride
CAS No.	887266-90-2
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	3-Bromo-5-fluorobenzoic acid chloride; 5-Bromo-3-fluorobenzoyl chloride; Benzoic acid, 3-bromo-5-fluoro-, chloride; 3-Bromo-5-fluorobenzoyl chloride; (3-Bromo-5-fluorophenyl)carbonyl chloride; m-Bromo-m-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.