Description

1-(2-Isothiocyanatoethyl)-1H-Indole is a specialized indole derivative functionalized with a reactive isothiocyanate group. This compound is a valuable synthetic intermediate for the development of novel bioactive molecules and advanced materials. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and life science sectors for applications such as medicinal chemistry, chemical biology, and high-throughput screening.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Chemical Biology Probe Synthesis: Used to create affinity probes and activity-based protein profiling (ABPP) reagents due to its reactive isothiocyanate moiety, which covalently binds to amino groups.
• Agrochemical Research: Employed in the discovery and development of new pesticides and plant growth regulators.
• Material Science: Acts as a precursor for functionalized polymers and advanced organic materials with tailored properties.
• Academic & Contract Research: Essential for fundamental organic synthesis research and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1-(2-Isothiocyanatoethyl)-1H-Indole
CAS No.	887202-51-9
Molecular Formula	C11H10N2S
Molecular Weight	202.27 g/mol
Synonyms	1-(2-Isothiocyanatoethyl)indole; 1H-Indole, 1-(2-isothiocyanatoethyl)-; 2-(1H-Indol-1-yl)ethyl isothiocyanate; N-(2-Isothiocyanatoethyl)indole; 1-(Isothiocyanatoethyl)indole
EINECS	Contact for details

Quality Control

Our 1-(2-Isothiocyanatoethyl)-1H-Indole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.