Description

1-(2-(Difluoromethoxy)Phenyl)Ethan-1-Ol is a high-value fluorinated aromatic alcohol building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its difluoromethoxy phenyl moiety imparts desirable metabolic stability and bioavailability. It is primarily utilized by research and development chemists and process scale-up teams in the life sciences and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the fluorine atoms for enhanced efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex molecular architectures.
• Material Science Research: Investigated for incorporation into polymers and advanced materials to modify surface properties and stability.

Basic Information

Product Name	1-(2-(Difluoromethoxy)Phenyl)Ethan-1-Ol
CAS No.	886859-40-1
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	1-[2-(Difluoromethoxy)phenyl]ethanol; 2-(Difluoromethoxy)phenethyl alcohol; α-Methyl-2-(difluoromethoxy)benzenemethanol; 1-(2-(Difluoromethoxy)phenyl)ethanol; (RS)-1-[2-(Difluoromethoxy)phenyl]ethan-1-ol; 886859-40-1; Ethan-1-ol, 1-(2-(difluoromethoxy)phenyl)-
EINECS	Contact for details

Quality Control

Our 1-(2-(Difluoromethoxy)Phenyl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.