Description

3,5-Dimethyl-2,4,6-Trifluorobenzoyl Chloride is a highly functionalized benzoyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of electron-withdrawing fluorine atoms and the reactive acid chloride group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic cores for advanced electronic display and lighting materials.
• Polymer Chemistry: Monomer for creating specialty polymers with enhanced thermal stability and chemical resistance.
• Cross-Coupling Reactions: Serves as an electrophile in palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Peptide & Protein Research: Acylation reagent for modifying amino acids or introducing fluorinated aromatic groups into biomolecules.

Basic Information

Product Name	3,5-Dimethyl-2,4,6-Trifluorobenzoyl Chloride
CAS No.	886762-25-0
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	2,4,6-Trifluoro-3,5-dimethylbenzoyl chloride; 3,5-Dimethyl-2,4,6-trifluorobenzoic acid chloride; 2,4,6-Trifluoro-3,5-dimethylbenzoic acid chloride; 886762-25-0; 3,5-Dimethyl-2,4,6-trifluorobenzenecarbonyl chloride; TFMB-Cl (common abbreviation); α,3,5-Trimethyl-2,4,6-trifluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dimethyl-2,4,6-Trifluorobenzoyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for high-purity intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.