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2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethanol CAS NO 886761-80-4


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CAS No.:886761-80-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethanol is a high-value fluorinated aromatic alcohol building block. This compound matters for its unique structure, which combines a phenyl ethanol core with fluorine and trifluoromethyl substituents, offering significant potential for modulating the physicochemical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly where fluorination is used to enhance metabolic stability, bioavailability, or membrane permeability.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
  • Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display materials and organic light-emitting diodes (OLEDs).
  • Polymer Modification: Acts as a monomer or chain modifier for creating specialty polymers with tailored surface properties, chemical resistance, or optical characteristics.
  • Organic Synthesis Building Block: The hydroxyl and aromatic groups provide handles for further functionalization, making it a versatile intermediate in complex multi-step synthetic routes.
  • Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new chemical entities and reaction methodologies involving fluorinated aromatics.

Basic Information

Product Name 2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethanol
CAS No. 886761-80-4
Molecular Formula C9H8F4O
Molecular Weight 208.15 g/mol
Synonyms 2-(4-Fluoro-3-(trifluoromethyl)phenyl)ethan-1-ol; 4-Fluoro-α,α,α-trifluoro-m-tolyl ethanol; 1-(4-Fluoro-3-(trifluoromethyl)phenyl)ethanol (tautomer); 2-(4-Fluoro-3-trifluoromethylphenyl)ethanol; 4-Fluoro-3-trifluoromethylphenethyl alcohol; F3C-Ph(F)-CH2CH2OH; [4-Fluoro-3-(trifluoromethyl)phenyl]ethanol
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Quality Control

Our 2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Ethanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Purity (HPLC/GC) ≥ 97.0% (Standard Grade)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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