Description

4,5-Difluoro-2-Methoxybenzyl Alcohol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methoxy and alcohol functional groups, which are crucial for modulating the physicochemical and biological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-methoxybenzyl motif can enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies.
• Functional Material Development: Employed in creating specialty polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Research & Development: A versatile building block for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	4,5-Difluoro-2-Methoxybenzyl Alcohol
CAS No.	886761-72-4
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2-(Hydroxymethyl)-1,4-difluoro-5-methoxybenzene; (4,5-Difluoro-2-methoxyphenyl)methanol; 4,5-Difluoro-2-methoxybenzenemethanol; 2-Methoxy-4,5-difluorobenzyl Alcohol; 4,5-Difluoro-o-anisyl Alcohol; 886761-72-4; 4,5-Difluoro-2-methoxybenzylalcohol
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Methoxybenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.