Description

4-Bromo-3-Chloro-2-Fluorophenyl Isothiocyanate is a high-purity, multi-halogenated aromatic isothiocyanate building block of significant importance in advanced organic synthesis. Its reactive isothiocyanate group and unique halogen substitution pattern make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Chemical Biology Probe Development: Serves as a versatile reagent for creating activity-based probes (ABPs) to study enzyme function and mechanism.
• Material Science Research: A precursor for synthesizing specialized polymers and liquid crystals with unique electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring specific halogenated phenyl isothiocyanate motifs.

Basic Information

Product Name	4-Bromo-3-Chloro-2-Fluorophenyl Isothiocyanate
CAS No.	886501-37-7
Molecular Formula	C7H2BrClFNS
Molecular Weight	282.52 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-4-isothiocyanatobenzene; 2-Fluoro-3-chloro-4-bromophenyl isothiocyanate; 4-Bromo-3-chloro-2-fluorophenyl mustard oil; (4-Bromo-3-chloro-2-fluorophenyl)isothiocyanate; Isothiocyanic acid, 4-bromo-3-chloro-2-fluorophenyl ester; NSC 886501
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-2-Fluorophenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.