Description

4-Chloro-3-(Trifluoromethoxy)Benzoyl Chloride is a high-value aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethoxy substituents, makes it an essential precursor for creating compounds with tailored electronic and steric properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of molecules with fluorine-containing motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs), leveraging its aromatic core and halogenated groups.
• Polymer Chemistry: Acts as a monomer or modifying agent in the creation of high-performance polymers and resins with specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on proprietary compounds for clients.
• Research & Development: Employed in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	886500-55-6
Molecular Formula	C8H3Cl2F3O2
Molecular Weight	259.01 g/mol
Synonyms	4-Chloro-3-(trifluoromethoxy)benzoyl chloride; 4-Chloro-alpha,alpha,α-trifluoro-3-methoxybenzoyl chloride; 3-Trifluoromethoxy-4-chlorobenzoyl chloride; 4-Chloro-3-trifluoromethoxybenzoic acid chloride; Benzoyl chloride, 4-chloro-3-(trifluoromethoxy)-; 886500-55-6
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-(Trifluoromethoxy)Benzoyl Chloride adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We operate under a quality system designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines. Due to its reactivity as an acid chloride and sensitivity to moisture, containers must be kept sealed under an inert atmosphere (e.g., nitrogen) after initial opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.