Description

2-Methoxy-4-(Trifluoromethyl)Benzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the methoxy and trifluoromethyl substituents, which impart desirable electronic and steric properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable and high-quality intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the 2-methoxy-4-(trifluoromethyl)benzoyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of specialty monomers and polymers, including liquid crystals and high-performance engineering plastics.
• Material Science Research: Utilized in the development of novel organic electronic materials and dyes.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethyl)Benzoyl Chloride
CAS No.	886500-49-8
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	4-(Trifluoromethyl)-2-methoxybenzoyl chloride; 2-Methoxy-α,α,α-trifluoro-p-toluoyl chloride; 2-Methoxy-4-trifluoromethylbenzoyl chloride; 4-Trifluoromethyl-2-methoxybenzoic acid chloride; 886500-49-8; p-(Trifluoromethyl)-o-methoxybenzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.