Description

2-Chloro-6-Fluoro-3-Methoxybenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate essential for advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought by R&D and production chemists in the pharmaceutical, agrochemical, and advanced material science industries for constructing complex active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides where the chloro-fluoro-methoxy pattern confers specific biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating complex aromatic cores in electronic display and lighting materials.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polyamides, polyesters, and other high-performance polymers.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for Friedel-Crafts acylation, amide coupling, and other nucleophilic substitution reactions.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized colorants with enhanced lightfastness and chemical stability.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methoxybenzoyl Chloride
CAS No.	886499-44-1
Molecular Formula	C8H5Cl2FO2
Molecular Weight	223.03 g/mol
Synonyms	2-Chloro-6-fluoro-3-methoxybenzoyl chloride; 3-Methoxy-2-chloro-6-fluorobenzoyl chloride; 886499-44-1; Benzoyl chloride, 2-chloro-6-fluoro-3-methoxy-; 2-Chloro-6-fluoro-m-anisoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Methoxybenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.