Description

3-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate essential for advanced organic synthesis. This compound matters for its role in introducing the 3-fluoro-4-(trifluoromethoxy)benzoyl moiety, a key structural motif that enhances the biological activity and physicochemical properties of target molecules. It is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients, particularly in the development of herbicides, pharmaceuticals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Crucial precursor in the manufacture of modern herbicides and pesticides, where the fluorine and trifluoromethoxy groups contribute to efficacy and environmental stability.
• Liquid Crystal & OLED Material Production: Used in the synthesis of advanced electronic materials for displays and lighting applications.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with unique thermal and chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs developing novel compounds for clients.
• Research & Development: Employed in academic and industrial labs for medicinal chemistry programs and material science research.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	886499-09-8
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	3-Fluoro-4-(trifluoromethoxy)benzoyl chloride; 4-(Trifluoromethoxy)-3-fluorobenzoic acid chloride; 3-Fluoro-4-trifluoromethoxybenzoic acid chloride; 886499-09-8; α,α,α-Trifluoro-3-fluoro-4-methoxybenzoyl chloride?; Benzoic acid, 3-fluoro-4-(trifluoromethoxy)-, chloride; TFMB-Cl (common abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethoxy)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.