Description

2,6-Difluoro-3-Methoxybenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and methoxy substituents, which are essential for modulating the biological activity and physicochemical properties of target molecules. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro-methoxy motif enhances lipophilicity and systemic activity.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing mesogens used in display technologies.
• Polymer Chemistry: Employed in the production of specialty polyesters and polyamides with unique thermal and chemical resistance properties.
• Organic Synthesis Reagent: A versatile reagent for introducing the 2,6-difluoro-3-methoxybenzoyl moiety into complex molecules via amidation or esterification reactions.
• Chemical Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) in drug discovery.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzoyl Chloride
CAS No.	886498-40-4
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	3-Methoxy-2,6-difluorobenzoyl chloride; 2,6-Difluoro-3-methoxybenzoic acid chloride; 2,6-Difluoro-m-anisoyl chloride; 886498-40-4; Benzoyl chloride, 2,6-difluoro-3-methoxy-; 2,6-Difluoro-3-methoxybenzoylchloride
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxybenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.