Description

2-Fluoro-5-(trifluoromethoxy)benzoyl chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its ability to introduce the 2-fluoro-5-(trifluoromethoxy)benzoyl moiety, a key structural motif that enhances the biological activity and physicochemical properties of target molecules. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups contribute to efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce functional aromatic groups into polymer chains, modifying thermal stability and chemical resistance.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences sector.
• Research & Development: Used in academic and industrial labs for methodological development and exploring new chemical entities.

Basic Information

Item	Details
Product Name	2-Fluoro-5-(Trifluoromethoxy)Benzoyl Chloride
CAS No.	886497-89-8
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	2-Fluoro-5-(trifluoromethoxy)benzoyl chloride; 5-(Trifluoromethoxy)-2-fluorobenzoyl chloride; Benzoyl chloride, 2-fluoro-5-(trifluoromethoxy)-; 886497-89-8; 2-Fluoro-α,α,α-trifluoro-p-methoxybenzoyl chloride (related); 2-Fluoro-5-trifluoromethoxybenzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(trifluoromethoxy)benzoyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.