Description

3-Chloro-5-Fluoro-4-Methoxybenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its specific halogen and methoxy substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a reactive benzoyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated aromatic structure.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and polyesters.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce the 3-chloro-5-fluoro-4-methoxybenzoyl group.
• Dye and Pigment Intermediate: Used in the production of complex, high-performance colorants.

Basic Information

Product Name	3-Chloro-5-Fluoro-4-Methoxybenzoyl Chloride
CAS No.	886497-26-3
Molecular Formula	C9H5Cl2FO2
Molecular Weight	247.04 g/mol
Synonyms	3-Chloro-5-fluoro-4-methoxybenzoyl chloride; 4-Methoxy-3-chloro-5-fluorobenzoyl chloride; 886497-26-3; 3-Chloro-5-fluoro-4-methoxybenzoic acid chloride; 3-Chloro-5-fluoro-p-anisoyl chloride; Benzoyl chloride, 3-chloro-5-fluoro-4-methoxy-; 5-Fluoro-3-chloro-4-methoxybenzoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-4-Methoxybenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from moisture, strong bases, and oxidizing agents. Under these conditions, the product is stable for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.