Description

3-Chloro-5-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 3-chloro-5-fluorobenzoyl moiety, a key structural motif in the development of active pharmaceutical ingredients and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzoyl group.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern enhances bioactivity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the production of specialty polymers and high-performance materials, such as polyamides or polyesters, with unique thermal and chemical resistance properties.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and pigments.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on medicinal chemistry and new material science.

Basic Information

Product Name	3-Chloro-5-Fluorobenzoyl Chloride
CAS No.	886496-62-4
Molecular Formula	C7H3Cl2FO
Molecular Weight	193.00 g/mol
Synonyms	3-Chloro-5-fluorobenzoic acid chloride; 5-Fluoro-3-chlorobenzoyl chloride; Benzoic acid, 3-chloro-5-fluoro-, chloride; 3-Chloro-5-fluorobenzoyl chloride; 886496-62-4; 3-Chloro-5-fluoro-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Store away from incompatible materials such as strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.