Description

[1-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is a high-value fluorinated organic building block characterized by its unique cyclopropyl and trifluoromethylphenyl structure. This compound matters for its role as a versatile intermediate in the synthesis of advanced molecules, where its specific geometry and fluorine content are critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where the cyclopropyl ring introduces rigidity.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethylphenyl moiety into more complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	[1-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol
CAS No.	886366-41-2
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	[1-(3-(Trifluoromethyl)phenyl)cyclopropyl]methanol; (1-(3-(Trifluoromethyl)phenyl)cyclopropyl)methanol; α-(3-Trifluoromethylphenyl)cyclopropanemethanol; 1-(3-Trifluoromethylphenyl)cyclopropanemethanol; (1-(m-Trifluoromethylphenyl)cyclopropyl)methanol; 886366-41-2; Benzeneethanol, α-(3-(trifluoromethyl)phenyl)cyclopropyl-; Cyclopropanemethanol, 1-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our [1-(3-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for reliable, batch-to-batch consistency required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.